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Except for the few differences in instrumentation mentioned below, the protocol and reagents used for size exclusion chromatography (SEC) and for the IEC were the same.
As discussed in the paper, differences of methodology and types of patients enrolled in each individual trial may account for the few differences reported among the biologics.
Similar(58)
The few differences observed for mispaired complexes (e.g., the higher fluorescence signal for G-dGTP with Y766F) could indicate either that mutation of Y766 alters the DNA conformation around the templating base in particular complexes or that the DNA conformation is the same but the mutated 766 side chain affects the 2-AP fluorescence signal.
The pre-admission characteristics that we measured were broadly similar and it is unlikely that the few differences observed account for contrasting outcomes.
On closer inspection, I cannot help feeling that for the few genuine differences that exist, there are also many hypothetical ones.
For example, due to the very few differences in the 5'- and 3'-UTRs, between the two parental viruses, a nucleotide substitution in either UTR that may result in a more homogenous interaction, as seen with either parental virus, may result in an increase growth rate.
Azimuthal distribution analysis of both the measured structures and drainage channels shows similar trends, except for very few differences in the prevailing directions.
The order and morbidity rates of top 10 causes for sex- and age-specific groups are similar to those of the entire population except for a few differences.
The report found that the sex of a child accounted for very few differences in a mother's spending, with two exceptions: video games, where boys' mothers devoted more than double the share of their spending that girls' mothers did; and clothing, where girls' mothers allocated 26percentt of their spending, while boys' mothers allocated 20percentt.
When considering indication for use and regimens for administration, very few differences were observed between the pre-specified subgroups.
Except for a few differences, she said, her program was essentially the same as Parkshore's.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com