Sentence examples for for the discovery and validation of from inspiring English sources

High affinity antibodies are crucial both for the discovery and validation of biomarkers for human health and disease and as clinical diagnostic and therapeutic reagents.

Here, we report an affinity proteomicstrategy for the discovery and validation of AMPK targets using an antibody to isolate proteins containing the phospho-AMPK substrate recognition motif from hepatocytes that had been treated with pharmacological AMPK activators.

SNPs can be extremely valuable molecular markers but effort is required for the discovery and validation of SNPs, as well as for assay development.

Overall, the death-switch model represents a robust and versatile tool for the discovery and validation of apoptosis biomarkers.

New developments in protein profiling techniques hold promise for the discovery and validation of relevant disease markers.

Our preclinical death-switch model allows tightly controlled induction of apoptosis in vivo with demonstrable application for the discovery and validation of biomarkers of cell death.

The discovery and validation of biomarkers for AKI will improve the early diagnosis of tubular injury, thereby facilitating timely therapeutic intervention.

An urgent OVCA research priority is the discovery and validation of biomarkers useful for diagnosing the most deadly types of OVCA, which often progress rapidly [3].

In this context, the discovery and validation of new biomarkers for septic shock development is regarded as a major research objective in the field [ 3, 4].

Multiple worm PD models, notably the toxin-induced models, have aided in the discovery and validation of potential pharmacological interventions for PD.

This effort has included the discovery and validation of new biomarkers of AKI.