Sentence examples for for the development of highly Pin1-specific from inspiring English sources

Therefore, there is a need for the development of highly Pin1-specific inhibitors.

Recently, functional and biochemical studies have provided the basis and rational for the development of highly specific and nontoxic BCL6 inhibitors (Basso and Dalla-Favera, 2012; Cerchietti and Melnick, 2013).

Altogether, this makes intrabodies a very promising tool for the study of protein function in vivo [ 6] and for the development of highly specific therapies [ 7].

Our findings suggest a potential novel strategy for the development of highly specific structure-based inhibitor for the prevention of colonic tumor progression.

Aptamers are thus suitable molecular probes for the development of highly-specific diagnostics for detecting STIV infections.

The development of highly specific agonists and antagonists for ET-1 receptors has provided tools for studying the role of ET-1 in tumour vasculature.

Significant progress in the understanding of HSV-2 infection has occurred due to the development of highly sensitive and specific serological tests (for the detection of HSV type-specific antibodies) [ 4].

Microresonator-based biosensors incorporating specific biorecognition probes are promising for the development of highly sensitive bacterial detection sensors.

Thus, detection of this mutation is valuable for the differential diagnosis of WM from these low-grade B-cell neoplasms, leading to the development of highly sensitive allele-specific PCR (AS-PCR) methods to detect specifically the MYD88 L265P mutation.

The development of highly sensitive, species specific PCR based methods of diagnosis [ 9] provides the possibility of more comprehensive data on prevalence.

The high specificity and avidity of the produced antibody enabled the development of highly specific and sensitive ELISA for the accurate determination of ROS in plasma without pretreatment at concentrations as low as 40 pg/ml.