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Pre-clinical considerations for the development of a targeted host-directed therapy are discussed here.
This information demonstrates the potential applications of ALS for the development of a targeted phytosanitary approach for the management of P. ramorum.
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An urgent need exists for the development of a new strategy for targeted cancer therapy.
Understanding this will have implications for the development of novel anticancer targets that target the initiation of DNA replication [12].
This review will describe recent approaches for the development of targeted liposomes.
Therefore, Nupr1 appears as a seducing target for the development of a therapeutic strategy against PDAC.
Further improvement will have to wait for the development of specific targeting strategies.
Neurotoxicity is a major limitation for the development of drugs that target the brain.
An improved understanding of pathophysiological mechanisms is a prerequisite for the development of new treatment targets.
These are now attractive targets for the development of vaccines that directly target DC in vivo.
The development of a biomarker for HAD development could also aid in the development of drugs to target HAD-specific viruses.
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