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These results indicate that RhoE expression is necessary for survival as well as for the correct development during the postnatal period.
These developmental pathways involve complex networks of genes, the precise regulation of which is vital for the correct development of the gonads and associated anatomical structures [1].
Lhx6 is expressed by, and required for, the migration of GABAergic neurons during development [33], while Dlx1, together with its family member Dlx2, is necessary for the correct development of many GABAergic neurons [24].
More recently, a genetic analysis in this organism indicated that, while the subunits of the Cdk8 module are not essential for cell viability, they are all necessary for the correct development of the multicellular organism [12].
We used three types of mutants: (1) cilium structure mutants which have defects in the sensory endings of ciliated sensory neurons, (2) sensory transduction mutants which lack components necessary for signal transduction, and (3) neuron specification mutants which lack transcription factors that are necessary for the correct development and function of specific neurons.
BMP7 is a central mediator of epithelial mesenchymal interactions that are necessary for the correct development of structures belonging to the oro-facial complex.
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The advantages afforded by breastfeeding have been reported in the literature and include the well-established immunological and psychological benefits, adequate weight gain for the baby, and the correct development of the oral structures involved in the action of sucking.
The localization of Hsp60-like BBS proteins at the cilium basal body and at the centrosome [ 26- 28] suggests that they may also interact and associate with, for example, cytoskeleton structures in promoting the correct development of cilia [ 28, 57].
These results demonstrate that DmPsGEF is necessary for the correct axonal development of alpha/beta neurons in MBs.
Here, we analyze the phenotype of RhoE null mice and show that RhoE is essential for a correct development since the absence of RhoE expression induces severe behavioral and structural alterations and becomes deleterious few weeks after birth.
Signalling between the visceral mesoderm, which develops into smooth muscle and other specialized tissues in the gut wall, and the gut endoderm, which provides the epithelial cell lining of the gastro-intestinal tract, is critical for correct development of the gut [37].
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