Although the initial clinical trials with bapineuzumab failed to achieve the clinical end-points at the disease stage tested [ 11], the continued refinement of Aβ targeted immunotherapy for AD has resulted in numerous follow-on passive and active immunotherapy approaches currently undergoing clinical investigation.
What might keep these kinds of predictions from seeming ridiculous 20 years from now is that they don't require huge theoretical breakthroughs -- just the continued refinement of technology that already exists.
Compared to the continued refinement of CDMA-based technologies in HSPAC, LTE has benefited from not requiring backward compatibility at the physical layer.
Looking ahead, well, there are there are the continued refinements and additional content that Harris alluded to.
These results suggest the need for continued refinement of magnetic techniques for purposes of erosion model validation and general sediment tracing applications.
As such, this construct should not be considered complete, but rather "fit-for-purpose" and suitable for continued refinement, expansion, and addition of influential components of interest (e.g., sclerostin, Wnt pathway, vitamin D kinetics and direct actions, metalloproteinases, etc).
A continued refinement of the NGS technology will further improve the sequencing accuracy and reduce the cost.
First, the coupling approach of a predictor and a descriptor is yet general and its full application for different cancer types will still require a continued refinement, as well as broadening the number of prognosis factors whose cancer-specific ones are then selectively included.
Through continued refinement and staged introduction the proforma and the process has demonstrated consistency from medical to surgical wards; introduction in new areas has rapidly improved results.
