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As the authors claim, a Cytoscape app for the alignment and visualization of PPI networks may serve as a useful tool for researchers working with multiple PPI networks.
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To the authors knowledge, it is the first Cytoscape tool for the computation and visualization of local alignments in a user-friendly way, without requiring any post-processing operations.
In particular, we concentrate on the use of Bioconductor tools for the representation, manipulation and visualization of alignments, including quantification, annotation and statistical modelling of the data.
We therefore present a potential supportive tool for PCa diagnostics since this allows for automated alignment and fast visualization of areas of interest on differently stained sections.
In this paper, we presented GASOLINE, an app for Cytoscape 3 for computation and visualization of multiple local alignments of protein-protein interaction networks.
To the best of our knowledge, it is the first Cytoscape plugin for computation and visualization of multiple local alignment of biological networks.
Alignment to individualized genomes presents a challenge for comparison and visualization of sample alignments; however, new tools make conversion back to reference genome coordinates straightforward (Huang et al. 2013).
We developed a pipeline for detection and visualization of alternative splicing in Chlamydomonas based on EST-to-genome alignments using BLAT [ 23], and a modified version of the Sircah alternative splicing detection software [ 24].
The MAUVE alignment tool was used for multiple genomes sequence alignment and visualization.
Multiple alignment of protein sequences and visualization of the detected post-translational modification sites were performed using CLC Sequence Viewer (CLC Bio).
It is, however, limited to computing all pair-wise alignments, with no post-processing and visualization of map alignments.
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