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The additional indication for malaria prophylaxis was obtained in 1994 with a supplemental New Drug Application.
Products granted marketing authorisation for an additional indication were counted twice, as an EPAR variation report is available for the new indication and PAMs can be clearly distinguished between the two indications.
In addition, we analyzed clonality of the Salmonella-specific T cell response using a TCR beta clonality assay, as an additional indication for antigen-specific T cell activation.
The authors also added positive family history of cirrhosis or hepatocellular carcinoma (HCC) as an additional indication for liver biopsy due to Thai national guidelines [ 6] (only 1 patient biopsied by this indication was included).
The finding of the 164L mutation is an additional indication for the high level of SP resistance.
In order to further increase the sensitivity and coverage of the search, one investigator (DJR) will also search the grey literature for additional indications not reported in the peer-reviewed literature.
Such accumulation, in the course from the injection site to the ventricle, is a strong additional indication for bulk flow from the parenchyma of the striatum.
Surprisingly, also the GRC shows a MLH1 focus in a minority of the nuclei (Fig. 2c), which provides an additional indication for the formation of meiotic DSBs in the GRC of some nuclei during leptotene.
Finally, an additional indication for the validity of the method is that no components of the DGC were identified.
An additional indication for the coexistence of the ZB and RS phases within one single shell is found in the dark field HRTEM images of a large core/shell NC after 3 h of exchange time.
This might be an additional indication for the need - already felt by the professionals - to improve coordination in Dutch midwifery and obstetrics.
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CEO of Professional Science Editing for Scientists @ prosciediting.com