Sentence examples for for targeted interference from inspiring English sources
In combination with functional analyses, structural information on these enzymes has therefore proven to be a valuable template not only for understanding their mechanism of catalysis, but also for targeted interference with substrate binding.
Its elucidation will certainly be labor intensive, but potentially rewarding since it increases the possibilities for targeted interference and the development of useful drugs.
A growth limiting step, in this case the activation of the estrogen receptor, can be identified and exploited for targeted interference.
By combining the therapeutic approach presented here with homing devices to, for example, target synoviocytes in the joint [ 37] or cells in the neointima in artery injury [ 38], a range of possibilities can be defined to explore the therapeutic benefit of targeted interference with different cells actively involved in joint destruction [ 39].
"I am particularly keen for the power for targeted equipment interference to be covered by a safeguard for sources.
Here, we discuss different modalities for targeted RNA interference with an emphasis on the potential applications of CRISPR/Cas systems as programmable transcriptional regulators for broad uses, including functional biology, biotechnology, and synthetic biology applications.
A role for BMDC-melanoma cell fusion in metastasis would imply that targeted interference of the fusion process or of rate-limiting post-fusion events might prevent invasion and metastasis.
And much of that qualification is appropriate: targeted interference is justified to protect life and limb.
In Xenopus embryos, targeted interference of BMP signaling does not affect cardiac specification, but reduces differentiated cardiac muscle and disrupts heart morphogenesis [9], [10].
In conclusion, our data show that targeted interference of either hyaluronan or heparan sulfate limits experimental metastasis suggesting that the net effect of the glycocalyx is pro-metastatic.
Conversely, the targeted interference with interactions of proteins or the interactions of proteins with DNA, important, for example, for the survival and proliferation of tumor cells, can be used for drug discovery and development.
