Sentence examples for for systemic administration from inspiring English sources

These results demonstrate the potential use of DNCs as a nano drug delivery system for systemic administration and controlled release of siRNA and potentially other sensitive bioactive macromolecules.

Here, we evaluated a newly designed hyaluronic acid (HA -shielded delivery system for systemic administration of plasmid DNA encoding MMP13 (pMMP13), and tested wHA -shieldednhancedeliverysystemforMP13 amelioratesystemicfibrosis in mice.

For systemic administration, novel delivery systems are required to confer "drug-like" pharmacokinetic and pharmacodynamic properties.

In addition to this, also systems originally intended for systemic administration, such as polymers and liposomes, have been shown to hold potential for such local interventions (Lammers et al, 2006).

CDF however has poor aqueous solubility and its dose escalation for systemic administration remains challenging.

The hydrogels were suitable for systemic administration of tolterodine for the treatment of overactive bladder.

These structures have low transformation efficiency and slight risk of toxicity at high-dose applications which are considered as promising vectors for systemic administrations.

The upper limit of FIZ-shFasL for safe systemic administration to rat is estimated as below 2 μg/ml in plasma concentration.

5-ALA-SQ presents a novel nano-delivery platform with great potential for the systemic administration of 5-ALA.

For example, systemic administration of laminin-111 to mdx mice results in deposition of the protein in the endomysium and reduces muscle membrane damage [77].

For the systemic administration of HVJ-E to treat cancer effectively, it must have high affinity for cancer cells and low affinity for sialic acids.