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For the brain to rewire itself it requires sustained practice of a new behavior which will sufficiently challenge the brain to think in a new way.
Although our substantive interest was in delirium prevention, the conceptual and methodological strategies pursued have implications for implementing and sustaining practice and service improvements more broadly.
Kneebone proposed 4 criteria to critically evaluate simulation training: Simulation should i) allow for sustained, deliberate practice within a safe environment; ii) provide access to expert tutors; iii) map onto real life clinical experience; and iv) provide a supportive, motivational, and learner-centred milieu.
However, although such an aggregate white-noise steady-state of demand would be desirable, it is unlikely to be achieved in practice for sustained periods.
Figure 1 Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient.
Figure 2 Suggested modifications to clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient.
In the clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient published in 2016 [5], NMBAs are suggested in ARDS patients with a ratio PaO2/FiO2 less than 150 (weak recommendation) but no dosage is mentioned.
Since the publication of the 2002 guidelines for the use of neuromuscular blocking agents (NMBAs) in the critically ill, titled "Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient" [1], there has been new evidence that clinicians must reconcile with their current understanding of which patients should receive NMBAs.
Since the publication of the 2002 guidelines for the use of neuromuscular blocking agents (NMBAs) in the critically ill, titled "Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient" [ 1], there has been new evidence that clinicians must reconcile with their current understanding of which patients should receive NMBAs.
First-generation Nigerian American artist, curator, and writer Nkiruka Oparah shares practical tools for sustaining a dream practice, as well as plants and herbs that can support self-integration and recentering.
Guided small group learning is used to promote participants' self-efficacy for sustained use of research evidence in practice.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com