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Some of the reasons mentioned for such gaps are because developing countries face shortages of financial resources, limited Internet access, a lack of trained teachers and the lack of proper policies.
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An in depth understanding of the barriers and facilitating factors responsible for such gap is important to improve adherence to CPGs in the LTC sector and to optimize the clinical care of elderly residents [ 8– 10].
There is no dedicated study that looked at assessment of suitable methods for infilling such gaps.
For instance, such gaps are found after dual incisions mediated by ERCC1-XPF during nucleotide excision repair and interstrand cross-link repair, also during mismatch repair downstream of EXO1 catalyzed removal of nucleotides, and subsequent steps following APE1-catalyzed DNA backbone cleavage in BER [21] [24].
For example, the Shanghai CFDA detected such gaps for both imported and domestic generics, where the rate of substandard quality was <0.1 and 3%%, respectively [ 7].
Patterns in stand-level growth, sapling recruitment and regeneration response were examined for one such gap-based system, the Acadian Forest Ecosystem Research Program AFERPP) in central Maine, that was designed to emulate the annual 1% disturbance frequency typical of the northeastern United States and Canada.
This is what my imagination is for - to fill in such gaps, to supply those details.
"There's no need for us to rush ahead to deal with an emerging threat," she said, referring to Iran's possible development of intercontinental missiles, "when we have such gaps now for the current threat".
In order to present an adequate source for reference sequencing and avoid such gaps at the sequence level, clone overlaps marked as 'unreliable' by LTC is reinforced with additional clones, as follows: For overlaps that were significant only at a cut-off of 10−14 or above, 210 additional clones covering the same overlap were picked manually.
For such big gaps, Nagarajan et al. proposed using other contig sequences for gap closures (their program called FINISH here) [ 12].
Such gaps are larger for the Brazilian Portuguese when compared to other languages, such as English, Spanish, and French.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com