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Furthermore, also providing benefit for subsequent interactions, optimization algorithms must be applied.
This CKII phosphorylation site is evolutionarily well-conserved among L1 orthologs and L1 family CAMs [45] and, therefore, is likely to be required for subsequent interactions of L1 proteins in signaling cascades and to serve a significant role in L1 function.
Although, atypical cooperators were infrequently punished in this setting, they were slightly less preferred for subsequent interactions.
The Cbl base-off state is thought to be important for subsequent interactions of Cbl with cytosolic cargo proteins.
Within the brain, apoE is synthesized primarily by glia, and secreted for subsequent interactions with members of the apoE family of receptors expressed by neurons and glia (Boyles et al., 1985; Pitas et al., 1987; Linton et al., 1991; Rapp et al., 2006).
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Furthermore, Foresight, it is claimed, should not only result in agenda-setting but also in creating durable communication channels for subsequent interaction between the participants.
Due to poor expression and stability of the Tob W93A mutant, we were unable to test the interaction of this mutant with CNOT7 in vitro, although the mutant expressed in mammalian cells for subsequent interaction assays in vivo.
Cell entry of HPV is initiated by binding of the virus particle to cell surface receptors, a prerequisite for subsequent interaction with the elusive uptake receptor, internalization and deliver of the genetic material into the nucleus of the target cell [16] [19].
Under physiological conditions, however, the presence of a ∼mM concentration of Ca2+ in the extracellular milieu would enable full occupancy of the site, thus indicating that the α- and β-Nrx expressed on the cell surface are pre-loaded with Ca2+ at the LNS6 domain and are ready for subsequent interaction with NLs.
For subsequent interaction experiments only growth on selective media (if any), where no growth of autoactivating clones occurred, was scored.
Activation of TLR4 also promotes receptor endocytosis with Rab11a, which causes a release of TLR4 for subsequent interaction with TRAM and TRIF 34.
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