These genes are obvious candidates for subsequent functional characterization and for research aimed at determining their function within infection processes.
Interpretation is based primarily upon the annotations from TIGR with additional corrections for genes for which subsequent functions have been defined, based upon literature searches of potentially significantly changed genes.
Rab proteins also contain a C-terminal prenylation motif, consisting of the last four amino acids; after translation, lipid modification occurs at this motif following geranylgeranylation, which is essential for targeting of Rabs to specific membranes, and thus for their subsequent function [ Pfeffer & Aivazian, 2004].
Indeed, a large number of man-made chemicals pose health risk as disruptors of signaling systems (intracellular, neural, and endocrine), which are required for normal development and subsequent functioning of organ systems that are already operating above threshold.
Combining these findings with functional genetic analysis has led to the conclusion that for most tissues a group of highly conserved genes is required for differentiation and subsequent function.
The molecular and cellular reagents created in this investigation provide a foundation for subsequent structure-function and inhibitor design studies on this key polyamine biosynthetic enzyme.
Initial cell adhesion and proliferation are critical for subsequent cellular functions.
SRPK1 efficiently phosphorylates the eight arginine serine repeats in RS1 driving SRSF1 into the nucleus for subsequent splicing function.
It allows for conservation of the uterus for subsequent menstrual function and pregnancies; hence it is preferred over hysterectomy [ 18, 19].
Biochemical, molecular and genetic studies have suggested that genes involved in GA metabolic and signaling pathways are essential for GA accumulation and subsequent functions [ 10– 10].
