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The three-ratio model has one ω ratio for branches ancestral to the duplication, one ω ratio for the two branches immediately following the duplication event and a third ω ratio for subsequent branches.
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Glucose metabolism in cancer cells is mainly through the glycolysis pathway, and several intermediates during glycolysis are used as substrates for subsequent branching biosynthetic pathways such as the pentose phosphorylation pathway and glycine serine synthesis pathways and so on.
The main branch of the model was designated for each treatment strategy to be investigated, with identical subsequent branches, with differences in probabilities as described above and with different resource use and costs.
The length of each fiber originating from each neuronal cell body and subsequent branches was measured, and a sum of total dendrite length for each neuron was calculated using Image Pro-plus software.
On the next four branches leading from the H-L branch towards the "top" of tree, RS becomes progressively higher, from 0.3→2.4→4.1→30→38 SSB, before diminishing on subsequent branches.
Losses were then placed on subsequent branches leading to any species not represented in the set.
For the MP analysis, a heuristic search was done using the stepwise addition algorithm for the provisional tree and subsequent branch swapping using the Nearest-Neighbor Interchange (NNI) method.
A subsequent branch-site test for selective pressure variation (see Experimental Procedures and Table S3) revealed that one substitution, D58S, may have undergone positive selection in the bowhead-whale lineage (with a posterior probability score of 0.983).
Secure tracing of their subsequent branching pattern was not always possible.
A subsequent branching separates two sister clades (B and A'D'G) both dated about 50 ka.
Development of RosettaDock diverged into two branches for subsequent CAPRI rounds as Jeffrey Gray, who laid the groundwork for RosettaDock while at the University of Washington, continued working on the method in his new position at Johns Hopkins University.
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