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Unfortunately, this combined sense of optimality is practically impossible to achieve, except for some trial types of bases.
229 230 231 A separate issue is that the trial protocol may not have been followed fully for some trial participants.
It is likely that decision aids could be more effective for some trial decisions rather than others for example, where interventions being trialled are very different (like medical management vs surgery), which is also the case for treatment decision aids.
Similar(57)
However, for some trials, manual editing of the MFR may be required.
Extensive evidence was found of errors, omissions, and contradictory entries in EUCTR data that prevented ascertainment of compliance for some trials.
For some trials they simply stared at the food location well before the food was placed there while on other trials they would engage the food and stare at it well before they initiated a reach.
For some trials, authors were contacted to obtain more information.
Application of foliar analysis in interpreting the results was made for some trials.
Therefore, in some cases, the control arms for some trials were included twice in the analysis.
For some trials, the authors were contacted for additional information on the results [ 8, 14].
However, they were also reduced to using 5-year survival estimates for some trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com