Exact(8)
However, for some interactions individual methods perform better than the consensus network (see Additional file 6A).
However, the results of PCC and SIREN are inconsistent for some interactions.
We generally used p < 0.05 to indicate statistical significance, except p < 0.10 was used for some interactions.
*Thermodynamic parameters for some interactions could not be fully characterized due to relatively low affinity, limited solubility of protein and limited availability of ligand.
When a variety of RR-leader peptide fusion proteins were used in combination with far-Western blot assays, it was shown that the fusion partner of the leader peptide was critical for some interactions between REMPs and their leader peptide.
It has been shown that in many instances, an integrative approach combining the outcome of each algorithm produces the best result [ 14], however, a detailed analysis shows that for some interactions individual methods perform better than the consensus network [ 15].
Similar(52)
Although both linear and two-term polynomial expressions are given for some interaction coefficients, it is recommended to use two-term polynomial expressions for interpolations.
For some interaction coefficients, especially those involving complexes, because experimental data on mean activity coefficient are lacking, they are tested against equilibrium quotients (see below).
Linear relations for some interaction coefficients might be used for extrapolations over a limited range of temperatures beyond the temperatures at which they are evaluated (say, over a limited range of ~25°C).
While two-term polynomial fittings can almost exactly reproduce interaction coefficients at various temperatures, linear fittings for some interaction coefficients can also reproduce interaction coefficients at various temperatures within uncertainty of 2σ as exemplified by the case for ε(Ca2+, Cl-) at various temperatures (Figure 2).
For some, interaction with others served only to highlight the intensity of their misery.
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