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A p-value < 0.01 and |log2 fold change| > 0.5 were set as cutoffs for significant different expressed genes, corresponding to the mean false discovery rate (FDR) around 10 - 13%.
After correcting for imbalances in baseline characteristics to be potentially prognostic for mRCC, known at the time these studies were done (performance status, number of metastatic sites, time from diagnosis to treatment (Palmer et al, 1992), and for significant different baseline characteristics between the two treatment cohorts (age, weight, prior therapy)) the s.c. and c.i.v.v
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One-way ANOVA was used to test for significant differences among different growth irradiances, using Tukey's multiple comparison tests to discriminate the means (MINITAB, Inc., Release 15, 2007).
Furthermore, multiple comparisons using a one-way ANOVA were employed to test for significant differences amongst the different severity grades.
The Kruskal-Wallis test was used to test for significant differences between the different groups of professionals.
Chi-squared tests and 95%% confidence intervals were used to test for significant differences between the different settings at baseline and follow-up.
The authors use p < 0.05 for significant differences and comparison between different age groups.
Contingency table and Wilcoxon-Mann-Whitney tests were used for significant differences among species reflecting different habitat preferences in both measures, respectively.
Corrected for the significant different patients characteristics as age, re-excision, histology, tumour size, and difference in time between lumpectomy axilla dissection, timing of RT (Table 1) showed a HR of 2.3 (95% CI 0.6 8.5; P=0.205) for the second tertile, and a HR of 1.2 (95% CI 0.3 6.4; P=0.761) for the third tertile compared with the first tertile.
The fact that even minimal chemical differences between fullerene 1 and 2 may be responsible for a significant different toxicity of these nanostructures, often defined as biocompatible and easy to handle with biological tissues, should be taken into due consideration.
For the 41 health self assessment items the response pattern was statistically significant different for 32 items (Additional file 2: Table B).
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