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For several substances (isothiazolones, anilides, diamidines, inorganic acids and their esters, alcohols), little information is available on resistance or tolerance [7].
Furthermore, the responses obtained in both tests, for several substances, had a good correlation with the available in vivo and in vitro data.
Recently, anti-tumoral potential has been proven for several substances that are not primarily used in cancer treatment.
Although the role of psychoactive substances in impairing driving ability is documented, the precise relationship between consumption and degree of driving impairment is not fully ascertained for several substances.
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The hazard index for a mixture of several substances Si (i = 1,2,…n) can be calculated as (9) The hazard index method does not allow prediction of the overall health effect of the combined substances but adds the strength of risk (roughly estimated), attributable to each component of the mixture.
A study was included in the review if: (1) it was a prospective cohort study; (2) there were at least two assessments of alcohol use between ages 10 17 in order to quantify change in alcohol use; (3) the total follow-up period was at least one year; and (4) data on alcohol use were presented separately but not if it only presented these data for the combined use of several substances.
Preventive drug therapies for CH include several substances (10, 11), but their use may be limited by intolerance or contraindications, and evidence of efficacy in CCH is poor.
Approximately 15% of the older population receiving drugs for mental disorders received several substances.
The database revealed several substances for which both human and rodent cytogenetic data existed.
Human follicular fluid contains several substances important for oocyte growth and maturation, such as estrogens, progesterone, FSH and androgens [ 34], proteins [ 35], amino acids [ 35], lipids (including free cholesterol and meiosis-activating sterol (FF-MAS)) [ 36, 37], and growth factors [ 38].
In the initial project phase, several substances were tested for their suitability.
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