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Red to Blue, which is seeking to raise about $200,000 apiece for selected candidates by hitting up donors in a process known as bundling, has identified more than 20 people it intends to help.
For selected candidates, differences in protein or protein isoform accumulation could be confirmed in Western blot experiments (Figure S1).
Additionally, using the Compara platform from Ensembl [ 69], phylogenetic trees for selected candidates were analyzed.
For selected candidates differences between the individual groups were tested by a Tukey HSD post hoc analysis.
In these settings MCA-Meth may serve as a technically easy and almost ubiquitously available initial screening tool, followed up by more sophisticated quantitative techniques for selected candidates.
Based on the analysis of cytokine deprivation-induced changes in mRNA expression levels of Bcl-2 family proteins, we determined the consequences of BH3-only protein depletion on HSPC survival in culture and, for selected candidates, on engraftment in vivo.
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Here we show that both study designs were comparable in their generation of robust median effective dose values for selected candidate drugs, as represented by similar confidence interval ratios.
We experimentally examined this coupling for selected candidate genes.
In addition, we performed a gene-based association test for selected candidate genes for migraine (Table 3 ).
We restricted our search to human symbols approved by HUGO Gene Nomenclature Committee (HGNC), which were enriched by all aliases and former (discontinued) symbols for selected candidate genes (http://www.genenames.org).org
Real-time quantitative reverse transcription PCR (RT-PCR) was performed for selected candidate genes that were upregulated (bmpD and clpP) or down-regulated (gene of membrane protein BB_0428 and rpmE) to validate the RNA-Seq data (see below).
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CEO of Professional Science Editing for Scientists @ prosciediting.com