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In an emergency situation, official media play the role of leader, leveraging the information and clarifying it, inducting public opinions, and making emergency under control, reducing the potential for secondary damage.
In an emergency situation, the authority plays the role of the manager, putting an announcement in the authoritative media to address rumors, inducting public opinions, and putting emergency under control, reducing the potential for secondary damage.
The temporal variation of these two parameters evaluated by continuous monitoring can establish whether the treatments used for patients receiving neurocritical care are properly tailored to the neurological changes induced by the lesions responsible for secondary damage.
With age, as contrasted with younger patients, raised intracranial pressure is considered less significant for secondary damage of the central nervous system while the significance of arterial hypertension/hypotension and cerebral hypoxia increases.
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The inhibition of activation of NF-kB has been demonstrated as a possible strategy for the attenuation of secondary damage in SCI [ 17, 18].
Most therapeutic approaches for SCI limit the development of secondary damage through neuroprotective measures for acute SCI.
The temporal variation of these two parameters, evaluated on the basis of continuous monitoring, can confirm whether the treatment is tailored to the neurological changes induced by the lesion responsible for the secondary damage.
To assess whether the reduced crypt survival in Rad21+/− mice is the result of intrinsic epithelial or secondary damage (for example, as a result of endothelial cell damage), we developed an ex vivo crypt survival assay using organoids established from isolated SI crypts.
In multi-axial loading experiments, the loading styles were deliberately designed for easier specimen recycling, avoiding secondary damage to samples.
Furthermore, markers associated with the pathophysiology of acute SCI should aid in monitoring the biological effects of a candidate treatment and also may identify potential targets for novel treatments that reduce secondary damage [5].
Although irradiation with light represents a clean and simple way of activating molecules in a spatiotemporally controlled way, the potential biological application of the strategy is limited by the low penetrability of the UV light typically used for photolysis and the likely secondary damage to the tissues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com