Sentence examples similar to for schedule dependent from inspiring English sources

Furthermore, support for schedule-dependent toxicity was recently given by Fuchs et al (2003).

This efficacy is schedule dependent, with a daily-for-8-days schedule being more efficacious than 4- and 1-day schedules.

Toxicity was highly schedule dependent: the recommended dose for the 3-weekly schedule (600 mg m -2)) was 30 tim -2that for the daily x 5 schedule (4 mg m(-2)day(-1)).

Temozolomide activity was schedule dependent and therefore oral administration was studied as a daily for 5 days schedule using total doses between 750 and 1200 mg/m in 42 patients.

Furthermore, the cytotoxic effects of camptothecins are highly schedule dependent.

Similarly, differences in cellular pharmacology following simultaneous and sequential exposure to XR5944 and SN38 or 5-FU may also be responsible for the observed schedule-dependent response to these agents in the HT29 cells.

In case of a virtual cluster in the Cloud, a batch submission system can be configured on demand for scheduling the jobs dependent on the virtual execution appliances available.

Preclinical data from rhabdomyosarcoma and neuroblastoma xenograft models have demonstrated schedule-dependent activity for irinotecan, with superior activity seen when using protracted low-dose administration (Houghton et al, 1995).

Similarly, the CHK1 inhibitors are active in cells with functional p53 and selectivity for p53 mutant cells may be schedule-dependent (reviewed in Ma et al, 2011).

Since several preclinical studies have shown a schedule-dependent drug interaction for the antimetabolites in combination regimens (Tolis et al, 1999; van Moorsel et al, 1999; Peters et al, 2000; Edelman et al, 2001; Symon et al, 2002; Giovannetti et al, 2004), we tested, in vitro, different treatment schedules.

In vitro models suggest schedule-dependent cytotoxic interactions for the combination of thymidylate synthase inhibitors with SN-38 and L-OHP; indeed, synergistic effects were demonstrated only when SN-38 was started 24 48 h before the L-OHP/5-FU/LV exposure in WIDR and SW620 human CRC cell lines (Fischel et al, 1999).