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A total of 139 subjects (n = 67 BAY 79-4980; n = 72 rFVIII-FS) comprised the study population evaluable for safety (intent-to-treat group) while 131 subjects were evaluable for efficacy (n = 63 BAY 79-4980; n = 68 rFVIII-FS; per protocol group).
The resulting fragility curves indicate that the life safety intent of the 2010 building designs has been met, while the same requirements could not be satisfied for the 1965 building designs.
All patients who received at least one dose of study medication were assessed for efficacy and safety (intent-to-treat population).
All patients who received at least one dose of study drug were evaluated for safety (modified intent-to-treat [mITT] population).
Each patient who received at least one dose of study drug was evaluated for safety (modified intent-to-treat [mITT] population) based on medical history and physical examinations, reports of clinical adverse events (AEs), and findings from 12-lead electrocardiograms (ECGs) and serum chemistry, haematology, and coagulation tests.
Analysis for safety was done on an intent-to-treat (ITT) population of subjects who received at least one dose and had at least a single post-baseline measurement.
Three primary populations of patients were assessed for safety, clinical, and bacteriologic outcomes; the modified intent-to-treat (mITT), microbiologic modified ITT m-mITTT), and the microbiologically evaluable (ME) populations.
All treated patients were included in the intent-to-treat (ITT) analysis and were analysed for safety.
All patients receiving at least one dose of ridaforolimus comprised the intent-to-treat (ITT) population, and all were assessed for safety.
"For safety".
"Buckle up for safety.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com