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CPB is one such modality that allows for safe resection.
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Slater et al. [8] recommended a distal margin of 1 cm and 2 cm for an oncologically safe resection in T1-T2 and T3-T4 tumourespectivelyely.
Albert Einstein The last one and a half decade has witnessed an exciting era for the management of advanced colorectal cancer, with emergence of effective combination chemotherapy, potent biologic agents, surgical techniques for safe hepatic resection and ancillary procedures such as portal vein embolization and radiofrequency ablation.
The median survival for GBM patients is <15 months after external beam radiotherapy and temozolomide after maximal safe resection (Stupp et al, 2005), whereas survival for most grade 3 patients is 2 3 years (See and Gilbert, 2004).
Thus, for patients aged 65 70 years with very favorable performance status, we recommend maximal safe resection followed by consideration of concurrent TMZ-based chemoradiation or a clinical trial if eligible.
An oncologically safe resection was proven by intraoperative frozen section.
A maximum safe resection approach is recommended, but not mandatory.
The tumor location should allow maximum safe resection.
Treatment consists of maximal safe resection followed by partial brain radiation.
However, if safe resection is not possible, biopsy to obtain a histological diagnosis is still indicated.
Maximal safe resection of a primary GBM is the mainstay of treatment and confers improved prognosis.
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