This underscores the importance of our approach; the methods used in most previous studies would find and report significance for parents' education levels (Deniz et al. 2008), or sex (Grose and Simpson 1982) (or age or ethnicity) in acceptance of evolution; in our study, however, these relationships appear to be driven by underlying variation in other variables.
The reported significance levels for the IBS distributions, LD and inbreeding have been Bonferroni-corrected for the number of tests done within each analysis.
Interestingly, 6 studies did not report significance testing for the total costs and the remaining 5 studies did not demonstrate a significant reduction of the total costs.
Our approach provided novel findings, replicated key results from prior analyses and provided unambiguous inference for functional annotations that previously reported significance levels that varied by dichotomization threshold.
In the 60 plus year history, articles on application of statistical reporting continue to encourage authors to present their findings [ 17, 19, 20], allow readers to interpret results [ 14, 17, 19, 20] and not use CIs strictly for reporting statistical significance [ 17, 20].
ANOVA (one-way analysis of variance and two-way analysis of variance) was used for the comparison among groups and for reporting the statistical significance ' p' with respect to the control group.
The adjusted alpha level for statistical significance for reporting such univariate associations was determined to be p < .004.004
Thus, regions containing only very rare causal variants are unlikely to produce GWAS signals that reach even nominal significance thresholds for reporting.
Harbord's test for reporting bias just reached statistical significance (P = 0.03).
