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Furthermore, the catalyst remains stable for repeated cycles.
The adsorption isotherms for repeated cycles showed a reduction in the amount of adsorption for the next cycles.
Data argue for repeated cycles of microaspiration and removal of bacteria in the lower airways of the CF patients in early life with the throat being the source.
However, at cycle 2 and subsequent cycles significant toxicities were observed, which indicated that this dose level was too toxic for repeated cycles.
Upon weaning, a process of involution destroys the majority of secretory epithelium, leaving the ductal tree extant for repeated cycles of growth and differentiation.
High foaling and seasonal pregnancy rates can also be hiding mares inseminated for repeated cycles, like several mares in our study, considering our first cycle pregnancy rate was 51.2%% overall and 42.2 % for cooled semen.
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There was also little cumulative toxicity with this regimen and patients tolerated repeated cycles for up to 3 years.
Additional images were obtained on day 28 of each repeated cycle for all patients remaining in the trial.
In this work we assume that the cycles are independent, but this assumption can be relaxed and random effects included to allow, for example, for repeat cycles from the same couples [ 15, 16].
PCRs were set up according to the following profile: an initial denaturation step of 94°C for 2 min, repeating cycles of 94°C for 30 seconds, annealing temperature given for each primer pair for 1 minute, and 72°C for 1 minute.
The aim of our retrospective evaluation was to assess the efficacy, consistency and safety of OnabotA for repeated treatment cycles administered regularly every 3 months in a population with severe CM and MOH.
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