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Furthermore, we strongly believe in the robustness of this approach for reliable function prediction and we envision its use in wide range of fields, other than biodegradation, to hopefully allow researchers to dive deeper in the functional properties of enzymes.
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Fluoropolymers have unmatched thermal and chemical stability, providing strength, resilience, and durability for the reliable function of a variety of products and industries.
According to a simulation experiment (Additional file 5: Figure S3A) minimum bit scores thresholds of 148, 110, and 74 can be used for phylogenetic and functional assignments at genus level (with >80% confidence level), phylogenetic and functional assignment at family level (with >80% confidence level), and for a reliable function (COG) assignment (with > 95% confidence level), respectively.
Our understanding of metagenomic samples is constrained by the large number of hypothetical proteins for which reliable functions are not available (Galperin & Koonin, 2004; Ellrott et al., 2010) and the high degree of misannotation of some functional families of proteins (Schnoes et al., 2009; Radivojac et al., 2013).
As expected, according to FunScore cutoff ( = 0.03) that was trained from other known protein-function pairs (Data S6), we preliminarily choose 425 more reliable function categories for 148 mitochondrial proteins within CoreMitoP.
Any S90 cluster which lacks at least one sequence with high-quality GO annotations is removed, as each family must contain at least one relative with reliable function annotations for annotation transfer to uncharacterized sequences.
Importantly, the method used in this model allows for reliable lung function data, such as lung compliance, to be sequentially collected in the same animals throughout the study.
The microelectrodes were characterized from the standpoint of properties important for corrosion applications, aiming at the reliable functioning during measurements.
Reliable functioning is crucial for the survival and development of the genetic regulatory networks in living cells and organisms.
The need for reliable and specific function in these environments may require more complex system designs than previously.
The removal of the excess heat by effective cooling technology is very vital for reliable operation, proper functioning and performance of thermal components, equipment and systems.
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