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Therefore, this platform could be used for recapitulating specific stem cell niches with the goal of improving tissue engineering.
Our unique strategy for recapitulating Alzheimer's disease pathology in a 3D neural cell culture model should also serve to facilitate the development of more precise human neural cell models of other neurodegenerative disorders.
The celebrated activist, who spent much of his short life promoting the theory that ideas should be freely available online to everyone, admonished Lessig for recapitulating his post to an audience of outsiders, telling Lessig: "That was private".
We compare two widely sequenced regions of the 16S rRNA gene to WMS sequencing for recapitulating skin microbiome community composition, diversity, and genetic functional enrichment.
Given the complexity of biological tissues, determining the most relevant parameters for recapitulating native structure function relationships through strategic biomimicry will reduce the burden for clinical translation.
Three-dimensional (3D) in vitro cultures are recognized for recapitulating the physiological microenvironment and exhibiting high concordance with in vivo conditions.
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For the purpose of recapitulating physical environments, perfusion culture conditions are applied to generate the mechanical forces that cells experience in living organisms.
Choice of optimal scaffold material is essential for properly recapitulating the tissue microenvironment.
Quiescent satellite cells are activated to reenter the cell cycle and to differentiate for repair, recapitulating features of myogenesis during embryonic development.
For example, tumors classified as a hormone-receptor positive subtype express estrogen receptor (ER or Esr1) and are generally dependent on estrogen for growth, recapitulating characteristics of a subset of normal, luminal epithelial cells found in the breast [ 6].
Notably, similar scenario might also exist in a recently published paper showing that both maternal and embryonic MMP9 are important for normal placenta formation at fetal-maternal interface and thus for embryo development, recapitulating our point that the development of embryo is inextricably linked to the uterine signaling, which, in this case, is governed by uterine Rbpj.
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CEO of Professional Science Editing for Scientists @ prosciediting.com