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To maintain assessor masking for questions relevant for all study participants, questions focused on the massage treatment (when relevant) will not be asked until all other questions have been completed and stored in the CATI database.
The approach has been used for research syntheses in health care, particularly for questions relevant to patient experiences of illness and care, such as lay experiences of chronic illness, of which there are now a number of published examples [ 4, 13, 14].
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We and others [26], [28] have shown that breast- and PrCa cell lines in 3D are representative for many questions relevant to tumor cell biology, rather poorly addressed in monolayer cell cultures.
It is acknowledged as a practical and feasible design while providing a systematic framework for answering questions relevant to 'real' clinical practice [ 23].
The highest item missing rate was for two questions relevant to the birth phase: 'Able to be referred to a medical specialist during birth care' (31.6%) and 'Consideration of home situation when planning appointments/examinations during birth care' (22.8%).
For this study, the questions relevant for the study question were selected from the questionnaire.
Alternatively, researchers may, for pragmatic reasons, wish to report an overall score for the seven questions relevant to all women.
Furthermore, they tackle questions relevant for policy making; they try to increase the awareness for the quality of the study design and the applied methodologies.
Note that some panel members answered only the questions relevant for helping children, some answered only the questions relevant for helping adults, and some completed both.
We also report on previous experiences and address open questions relevant for the theory and practice of MDWE.
Key research questions relevant for developing countries need to be answered early in the drug development process to ensure maximum benefit for the majority.
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