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This suggests that wild-type levels of the NANOS3 protein are required for proper regulation and expression of key regulators of germ cell development, meiotic progression and ectodermal differentiation.
We have recently shown that an intact chromosomal architecture of the c-myc regulator region is required for proper regulation of the c-myc gene by the FBPs [ 6, 7, 23].
Taken together, these data shed light on the importance of tight control of the functional interplay between ΔNp63 and p53 in regulating RUNX1 transcription factor expression for proper regulation of interfollicular epidermal homeostasis.
Thus, Sestrin2-mediated suppression of hepatic ER stress is not only required to prevent liver damage but also critical for proper regulation of lipid and glucose homeostasis.
Next month, the commissioner for internal markets, Michel Barnier, is to make an announcement on unfair trading practices, amid mounting pressure for proper regulation.
These findings come as part of an NUS campaign for proper regulation of letting agents, as well as proposing an end to letting fees.
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Decrees, laws and legislations are indeed necessary but not sufficient for the proper regulation of the market for CAM products.
Secondly, another possibility is that our transfected putative CysLT2R promoter is lacking crucial bindings sites for some enhancer/cofactor that is vital for its proper regulation.
The DAF-16 FOXO transcription factor is required for the increased stress resistance of egr-1 overexpression mutants, and egr-1 is necessary for the proper regulation of sod-3 (a reporter for DAF-16 activity).
As it is vital for the immune system to tolerate autologous structures for its proper regulation, any model of immunodominance should consider the potential impact of self/non-self discrimination.
Together, our results show that pRb is required for the proper regulation of OB- and N-cadherin expression in osteoblasts and for their assembly into stable adherens junctions.
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for proper supervision
for correct regulation
for sensible regulation
for proper adjudication
for proportionate regulation
for accurate regulation
for proper governance
for proper implementation
for proper organization
for proper management
for proper order
for public regulation
for proper installation
for emotional regulation
for proper preservation
for proper stealing
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