Sentence examples for for proper localization from inspiring English sources

In prior work, we showed that Dis3 and Rrp6 physically interact and co-localize in S2 cells and are mutually required for proper localization [ 13].

PHR proteins are characterized by the presence of two PHR domains near the N-terminus, which are essential for proper localization and function.

Interestingly, dnrx and dnlg1 mutants have reduced levels of the Bone Morphogenetic Protein (BMP) receptor Wishful thinking (Wit), and Dnrx and Dnlg1 are required for proper localization and stability of Wit.

Cell polarity and tissue architecture are intimately linked, as proteins controlling cell shape are also responsible for proper localization and assembly of cell cell junctions and three-dimensional tissue organization.

We found that Sch9 was not necessary for proper localization of GFP-Cdc5.

These results indicate that EWSR1 is required for proper localization of Aurora B during mitosis.

Interestingly, mutation of the Cdc5 NLS (and disruption of nuclear import machinery) also altered localization of Cdc5 to the SPB and the bud neck, suggesting that nuclear translocation of Cdc5 is indispensable for its function, especially prerequisite for its proper localization to the SPB and the bud neck.

We also show that VTI13 is important for the proper localization of SYP41, suggesting a role for VTI13 in maintaining TGN compartment identity through resident protein localization.

Collectively, our results demonstrate that the UVRAG and Atg6 containing PI3K (III) complex II is essential for the proper localization of membrane proteins and is required for the establishment of epithelial cell polarity, unlike the complex containing Atg14.

The fly gene nti is specifically required for the proper localization of Notch at the cell surface [ 26], is essential for the physical interaction of Notch with its ligand Delta, and is an essential component for neurogenesis [ 27].

Prenylation is a posttranslational modification essential for the proper localization and function of many proteins.