Sentence examples for for proper checkpoint from inspiring English sources

These malattachments escape the surveillance by the mitotic spindle checkpoint, indicating that Aurora-B kinases are also required for proper checkpoint function.

Mad1p Bub1p Bub3p complex formation is essential for proper spindle checkpoint function in yeast (Brady and Hardwick 2000).

Recent evidence revealed that DNA damage elicits alterations to the chromatin to facilitate proper checkpoint activation and DNA repair.

There weren't really any proper checkpoints; all I saw was traffic police in the streets.

A recent study revealed that actin polymerization is important for proper cell cycle checkpoint control in human cells (Hsu et al., 2010).

The cell cycle is a tightly regulated process, with each step carefully monitored by a specific group of proteins that act as checkpoints for proper cell division.

Analysis of genetic interactions between the msh4 –R676W hypomorph and spindle checkpoint genes MAD2, MAD3 suggest that the spindle checkpoint is not critical for proper segregation of the nonexchange homologous chromosomes in the msh4 –R676W hypomorphic background, but other mechanisms might still play a role.

Thus, mitotic exit network activity is important for proper kinetochore activity, and controls the spindle checkpoint (Tan et al. 2005).

ARTEMIS is known to be a phosphorylation target of ATR and ATM kinases and was found to be important for proper recovery from both S- and G2/M checkpoints [ 12, 14].

Similarly, KDM1A positively regulates the expression of MAD2 and BUBR1, which are part of the mitotic checkpoint complex and are required for proper chromosome segregation during mitosis [ 181].

In our previous studies concerning the mechanisms of the replication checkpoint, we found that Swi1 is required for proper activation of Cds1 in response to HU and for stabilization of replication forks in fission yeast [19].