This means that for poor alignments, MetaPSICOV will behave more like a standard machine learning-based contact prediction method, whereas for deep high-quality alignments more emphasis will be placed on coevolution signals.
As for geometric variation, on ramps in NEX are virtually allocated far from poor alignment like small curve.
"The second most common reason for injury is poor alignment, and that is usually crummy teaching".
A range of barriers prevented efficient and effective knowledge exchange among scientists and decision-makers including cultural differences among the groups, institutional barriers within decision-making agencies, scientific outputs that were not translated for decision-makers and poor alignment between research design and actual knowledge needs.
The amino acid substitution and composition in P. falciparum proteins were unusual and standard matrices (BLOSUM & PAM) did not detect orthologs and/or gave poor alignment for many P. falciparum proteins [ 9- 11].
This can be compared to a very poor alignment, for example 'disease – sjuk', which with a frequency of 1 will yield a qvalue of 0.0196 derived from 1/(48+3), given that 'disease' occurs in 48 and 'sjuk' in 3 different candidate term pairs.
Oracle has mastered takeovers but for most others, acquisitions can fail due to a poor alignment of vision for the industry and each company's role, cultural mismatch, geographic distance or lack of integration of systems (once you scale your number of acquisitions, having different divisions or subsidiaries use different software will make your CFO insane).
Regions of detected recombination were checked for spurious signals due to poor alignment, mapping, contig joins or low quality sequence.
In the Program Management area (n. 24 competencies) poor alignment has been identified for Infectious Diseases 37.5%,and Medical Microbiology UEMSS) 16.7% and Public Health Microbiology (EUPHEM) 4%.
For yvdR/ yvdS and ebrA/ ebrB sequences, poor alignment of three codons within the region encoding the first putative loop1 had to be removed.
