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It is equally important to assess the potential for outcome reporting bias at the systematic review level.
Objectives To provide information on the frequency and reasons for outcome reporting bias in clinical trials.
This review will assess study protocols for outcome reporting bias by judging whether authors have selectively reported outcomes using the Cochrane tool for assessing risk of bias.
No reviews overlapped in the two cohorts (they stemmed from non-overlapping time periods), and none of the studies assessed for outcome reporting bias were included in multiple reviews.
Moreover, we discovered that nearly a fifth of studies that underwent an assessment for outcome reporting bias had actually provided full data (which had somehow been omitted from the review) on the single primary harm outcome.
Owing to problems with recall bias in the earlier interview study 1 and because little emphasis was placed on harm outcomes, we plan in future to interview trialists about differences between outcomes specified in trial protocols and the trial report during the peer review process to better understand mechanisms for outcome reporting bias across both benefit and harm outcomes.
Similar(51)
If future studies could confirm the size of CLNM as an independent factor for outcomes, reporting the size of CLNM in the histopathology reports could become important.
Recent work [13] [19] has provided direct empirical evidence for the existence of outcome reporting bias.
ICC is around 4% for outcomes reported by written questionnaire and around 20% for outcomes reported by Video questionnaire.
For outcomes reported as continuous variables, means and standard deviations were extracted.
For outcomes reported as rates or proportions, a pooled estimate of the proportion will be estimated by weighting the studies according to their sample sizes (inverse variance).
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