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A similar trend was observed for outcome between JE and Non-JE patients in the +Lp group (P = 0.074).
Again, to account for the different effect sizes of this set of SNPs (OR 1.06 1.92) (Supplementary Table 1 A and B ), risk for outcome between the GRS30 groups was further quantified using the weighted GRS (results for the unweighted model are reported in Supplementary Table 1).
Given the range in the previously reported effect sizes for this set of SNPs (OR 1.08 1.92) (Supplementary Table 1 A and B ) risk for outcome between the GRS13 groups was further quantified using the weighted GRS13 (results for the unweighted GRS13 are reported in Supplementary Table 1).
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The sum of ICU therapeutic interventions was not discriminative for outcomes between elderly and less-old patients.
Means for outcomes between sites and order of condition were almost identical and thus neither of these factors were included in analyses.
Robust standard errors were used to account for interdependency of outcome between twins.
For qualitative outcomes, between-group comparison will be described by means of contingency tables and inferences with the Chi Square Test or Fisher's Exact Test.
A model adjusted for age and caries-risk indicator was used to test for outcome difference between the modified and conventional program groups after 18-month follow-up.
In all analyses, we calculated robust SEs clustered at the village level to allow for outcome correlation between children in the same village.
Baseline, 3- and 6-month values for outcome measures and between-group differences are presented as least-squares means and 95% CIs.
For these rehabilitation outcomes, between-group differences for participants with different OAI intervals were calculated using a Kruskal-Wallis analysis for non-parametric data.
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