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Study of MCT8 null-mice suggests that its expression is necessary for normal feedback regulation of TRH neurons in the hypothalamus [ 15, 16].
Levels of leptin in humans are log-linearly increased in relation to obesity [ 3] and lack of leptin induces severe obesity, demonstrating that leptin signaling is necessary for normal feedback control of body weight [ 4].
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As Fekete and Lechan stated, relatively stable levels of D2 activity in the mediobasal hypothalamus is necessary for normal negative feedback regulation of the HPT axis.
For this, we need a release of carbon dioxide that would overpower normal feedback mechanisms such as photosynthesis, so it has to be sudden.
Given the normal feedback it is quite possible.
In addition, auxin flux across the meristem is critical for normal patterning, with feedback between genes regulating auxin distribution and those regulating meristematic domains taking place.
Cheong, R. Y., Czieselsky, K., Porteous, R. & Herbison, A. E. Expression of ESR1 in glutamatergic and GABAergic neurons is essential for normal puberty onset, estrogen feedback, and fertility in female mice.
The reward function for the control network had two different feedback values, one for normal moving and one for the collision with the obstacles.
Study by Petersen and Barraclough (1989), described that sexually dimorphic region in the brain, namely the rostral preoptic area, is crucial for normal estrous cyclicity and estrogen positive feedback [ 57].
Homeostatic processes that provide negative feedback to regulate neuronal firing rates are essential for normal brain function.
Normal homes for normal people.
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