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The relationship between Hb levels and the risk of brain tissue hypoxia (BTH), defined as PbtO2 ≤ 15 mmHg, and metabolic crisis (MC), defined as lactate/pyruvate ratio ≥ 40 and glucose < 0.7 mmol/l, was analyzed with general linear models of logistic function for dichotomized outcomes utilizing generalized estimating equations for model estimation.
The parameters from the modeling exercise are validated using a hold-out sample not considered for model estimation.
These data are then used for model estimation.
Stated-preference driving simulator data is employed for model estimation.
The sample consisted of 9554 adolescent who yielded 20,432 SP responses for model estimation.
Simulations need to be performed before hand, using for example the software used for model estimation.
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The core consistency diagnostic has been successfully applied for CPD model estimation for decomposing epilepsy tensors [11, 13].
All five lag length criteria tested indicated 8 lags as the optimal model, so we consider it as the lag for our model estimation for all companies.
Data for years 1970 1994 have been used for the model estimation and years 1995 2002 have been used for validation.
Thus, the data set was reasonably sufficient for the model estimation.
This is required in order for the model estimation results to be interpretable.
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