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The mice were sacrificed 8 weeks later and assessed for minimal reconstitution in the bone marrow.
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Longitudinal analysis provided evidence of thymic emigration and reconstitution of CD45RA+CD31+CD4+ T-cells two years post-ART, but minimal reconstitution of the CD45RA+CD31-CD4+ subset, which could impair de novo immune responses.
We found that a structurally similar GEF, Cool2, also shows only minimal reconstitution (Fig. 4G).
How's this for minimal?
So much for minimal disruption.
Not all cases settle for minimal amounts.
Minimal effort for minimal reward: an American classic.
Aim for minimal contact.
For minimal formatting, choose Simple Text Box.
Use latex gloves for minimal mess.
Look for minimal, biodegradable and recyclable packaging.
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