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The term sleep restriction is commonly used for milder reductions of sleep duration continuing over weeks or longer.
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A recent neurologic examination revealed normal cognition, bilateral ptosis and intact external ocular movements, except for mild reduction of upward gaze.
The iron deficiency in PrPKO mice is mild since overt signs of anemia were not detected except for a mild reduction in hemoglobin levels, a significant reduction in serum iron, serum ferritin, and transferrin saturation, and an increase in the total iron binding capacity and the number of circulating reticulocytes.
This finding should encourage initiatives towards developing prophylactic strategies for patients who develop even mild reductions in kidney function.
Even pharmacological treatment has led, at best, to only mild reductions in hallucinations and delusions.
Mild reductions in platelet counts have also been described.
However, neurocognitive testing suggested only mild reductions in memory efficiency.
There is substantial evidence to support the central role of dopaminergic systems in the pathophysiology of RLS; for example a mild reduction in dopamine levels has been observed in the nigrostriatal pathway in patients with periodic limb movement disorder (PLMD) and RLS (Ruottinen et al. 2000).
Since the functionalization scheme relies on the presence of hydrogenated carbon atoms, we also explored the effect of sodium borohydride assisted mild reduction for improvements expected through an increase in antibody attachment.
This is used in mild reduction cases for women with smaller breasts where only minimal removal of skin is required.
We conclude that a mild reduction in the FiO2 for 3 days in rat pregnancy results in a significant fetal growth restriction that is not related to any observed alteration in maternal glucose metabolism.
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