Sentence examples for for mediating the function from inspiring English sources

Argonaute proteins are important for mediating the function of miRNAs.

To examine whether CD82 induction by ΔNp63 α is responsible for mediating the function of ΔNp63 α in inhibiting cell invasion, we ablated p63 expression and concomitantly expressed CD82 in FaDu and MCF-10A cells.

Furthermore, we identified in vivo correlations between the expression of p63 and direct target genes in HNSCC, suggesting that these genes are important for mediating the function of p63 in a tumorigenic environment.

Together, our findings suggest that Pak2 is the primary effector for mediating the functions of Rac and Cdc42 in T cell development and activation.

CCL2 signaling has been reported to mediate the migration of MDSCs [27] and arginase 1 is an important pathway for mediating the suppressor function of MDSCs [28].

Signal Transducer and Activator of Transcription (STAT) 3 is activated in response to cytokines and growth factors and it has been recently identified as a novel signal transducer for TrkA, mediating the functions of NGF in nervous system.

Further, the class III PI3-K hVps34, has shown to be localized at the endosome in addition to producing PI(3 -P only, making it a potential candidate for mediating SGK3 -Pnctionlyt the endosomaking

These findings are consistent with the notion that that miR-9 promotes a pattern of gene expression contributing to enhanced invasion and suggests a role for chymase in mediating the biologic functions of miR-9.

It is known that MCL-1 is expressed at high levels in prostate cancer and is important for mediating a survival function of the proinflammatory cytokine IL6 (Krajewska et al. 1996, Cavarretta et al. 2007).

The Janus kinase (JAK -signal transduction and activation of transcription (STAT) pathway is an essential cascade for mediating normal functions of different cytokines in the development of the hematopoietic and immune systems (Cheng et al. 2004).

The presence of FGFR1 is important for mediating SPARC functions in endothelial cells and skeletal myoblasts (Motamed et al, 2003).