In 2003, Pang et al. proposed a list of major functions for a national health research system, which was defined as 'the people, institutions, and activities whose primary focus is to generate high quality knowledge that can be used to promote, restore, and/or maintain the health status of populations.
On average, surveyed village communities valued both forests and farmlands for their food [collection of non-timber forest products (NTFPs), animal trapping] and direct income generation potential, although the importance given to farmlands for these major functions was more pronounced.
Finally, we show that Hdac6 is necessary for several major functions of Tip60-p400 in ESCs, as both Tip60- and Hdac6-deficient ESCs have defects in formation of single colonies, reduced proliferation rates, and defects in differentiation.
The prevailing general mechanism for vesicle budding in the secretory and endocytic pathways is the assembly on the donor membrane compartments of a 'coat', whose core and accessory subunits are responsible for two major functions: induction of bilayer deformation and protein cargo selection (Faini et al., 2013).
In addition, the insertion of an amber codon in a gene coding for a protein of major function (such as the highly conserved MtxX, Cas1 or the digeranylgeranylglyceryl phosphate synthase in the present case) might have turned the expression of the Pyl cassette and the efficient ability to incorporate Pyl essential for growth.
Previous study has shown that more than 50% of the miRNA genes are located in cancer-associated genomic regions or in fragile sites which are hot spots for gene deletion, amplification and mutations (Calin et al, 2004), suggesting major functions for miRNAs in cancer cell biology.
The paper introduces the conceptual framework advanced Learning Factory (aLF) highlighting its major functions for identifying learning modules, the module configuration, major interaction modes and transfer mechanisms in a generic learning factory.
They described two major functions for hyaluronic acid-TLR interactions in these processes.
Although Table 1 lists major functions for several proteins, it is important to remember that some of the functions are not totally understood or are not known at all [ 1].
