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Obesity is a potential risk factor for major complex diseases such as diabetes, cardiovascular diseases, metabolic syndromes as well as CP [ 8].
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Relative avidities of antigen-specific T cells for major histocompatibility complex peptide complexes (MHCp) have recently been measured by MHC tetramer dissociation assays, but there is no consensus on the methodologies used for these experiments.
Liquefaction of soils induced by the earthquake is one of the major complex problems for the geotechnical engineering.
The reduced extent and thickness of sea ice and the resultant longer open-water season have major, complex implications for the Arctic marine ecosystem.
They are known to biologists as M.H.C. genes, for major histocompatibility complex.
Numerous association studies have also provided evidence for major histocompatibility complex control of pathology in schistosomiasis.
The proposed structure presents backbone similarity with the native peptide especially at the N-terminus, which is important for major histocompatibility complex (MHC) binding.
Degradation products of the proteasome are not only used for recycling of amino acids but also exploited for major histocompatibility complex (MHC) class I antigen presentation to define the 'cell's self' towards the immune system [14].
We found that tumor eradication by T cells required high affinities of the targeted peptides for major histocompatibility complex (MHC) class I. Affinities of at least 10 nM were required for relapse-free regression.
The diagnostic importance of immunohistochemical staining for major histocompatibility complex I and II antigens, for the p62 protein, and of the recently identified anti-cN1A autoantibody in the serum, are discussed.
One hypothesis accounting for major histocompatibility complex (MHC) restriction by T cell receptors (TCRs) holds that there are several evolutionary conserved residues in TCR variable regions that contact MHC.
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