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Our approach uses software analysis to eliminate the need for maintaining allocation and free records.
To deal with this circumstance, the research fellow responsible for maintaining allocation concealment directs which intervention code numbers to use to provide the woman with additional trial medication, which preserves the same study group to which the woman was originally allocated.
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52 The following issues will be investigated: Methods for sequence generation and maintaining allocation concealment, blinding, incomplete outcome data and selective outcome reporting.
The risk of bias within each full-text trial will be assessed using the domains of the risk of bias tool as recommended by the Cochrane Collaboration, 26 which comprise methods for sequence generation and maintaining allocation concealment, blinding and management of incomplete outcome data.
Central randomisation by an independent allocator maintains allocation concealment.
Two trials at high risk of bias for sequence generation were included post hoc, but steps to maintain allocation concealment and blinding minimised the possibility that participants were treated differently between groups.
Therefore, the presence of methods to maintain allocation concealment was the only study quality factor used to assess for influence on the pooled effect estimate.
To maintain allocation concealment and minimise selection bias the dental assistants are unaware of the colour codes and block sizes used for randomisation.
We maintained allocation concealment until after we obtained written consent and completed baseline measures.
Randomizations occurred from 11 January 2001 to 29 October 2005 using permuted blocks to maintain allocation concealment.
Only 27percentt report that they maintain allocations to precious metals and even fewer (18 percent) are invested in foreign currencies.
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