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The 2010 Canadian Grand Prix had been a free-for-all, run in heavy rain that made for low grip, which meant a high number of overtaking moves, several pit stops for tire changes, and therefore unpredictable, exciting racing.
There was 100% concordance for low grip strength and hindlimb digit fusion in abnormal mice from this line and heterozygotes showed no abnormal phenotype (data not shown).
Cut points for low grip strength and slow walking speed were <30 kg (men)/ < 20 kg (women) and ≤0.8 m/s, as per the EWGSOP criteria.
The percentages of frailty components were 19.5% for low physical activity, 14.8% for unintentional weight loss, 18.6% for low grip strength, 18.3% for exhaustion, and 17.1% for slow gait speed (Table 2).
Participants with more than two chronic diseases and low muscle mass were more likely to perform poorly than those with no risk factors (OR = 2.51 for low grip strength, OR = 3.89 for slow gait, and OR = 3.67 for low TUG score, P < 0.05) after adjustment for confounding factors.
Compared with participants with no risk factors, the odds of poor physical performance among those having one chronic disease and low muscle mass were higher than among participants with two or more chronic diseases and normal muscle mass (OR = 2.42 vs. 1.90 for low grip strength, OR = 3.17 vs. 2.22 for slow gait, and OR = 3.08 vs. 2.80 for a low TUG score; P < 0.05).
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This imputation was only used for the definition of low grip strength.
For men, low grip strength was defined as ≤29 kg for men with a BMI of ≤24, ≤30 kg for men with a BMI between 24.1 and 28 and ≤32 kg for men with a BMI of >28.
For women, low grip strength was defined as ≤17 kg for women with a BMI of ≤23, ≤17.3 kg for women with a BMI between 23.1 and 26, ≤18 kg for women with a BMI between 26.1 and 29, and ≤21 kg for women with a BMI of >29.
The defect in the digits was not responsible for the low grip strength.
For these participants, low grip strength was determined using established grip strength values for sarcopenia (<20 kg for women and <30 kg for men) consistent with others [ 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com