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The objective of this study was to find determinants for low adherence to ART and program drop-out in a resource-poor, urban, sub-Saharan African setting.
This study seeks to assess program retention and to find determinants for low adherence to antiretroviral treatment (ART) and drop-out from an established HIV/ART program in Kibera, Nairobi, one of Africa's largest informal urban settlements.
Another important concern is the reasons for low adherence.
Adherence-related research has focussed on reasons for low adherence, manifested for example as barriers (3 5).
Reported factors for low adherence include low perceived esthetics, comfort, and therapeutic benefit of the shoes; higher BMI; and less severe foot deformity (12– 12).
Strategies to maximize adherence among subjects at greater risk for low adherence will be important for future trials, especially complementary treatments requiring greater effort than simple pill-taking.
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Among only those children who remained alive and in care for the entire first year of treatment (excluding those deceased and LFU; n = 88), the proportion with adherence <90% decreased over time with an OR for having low adherence of 0.91 (95% CI: 0.87 – 0.96; p = 0.000) for each additional month (figure 4).
Despite positive effects of regular physical activity on treatment outcomes and risk factors for relapse, low adherence and high attrition rates limit the benefits derived from exercise interventions.
For instance, low adherence has been reported as a key problem when treating young clients in community settings.
Such rigorous monitoring may be difficult in the challenging patient population that we studied, and could account for the low adherence to a certain extent.
The present study demonstrates that there is compelling evidence for a low adherence to HH guidelines in the OR setting and thus an urgent need for effective improvement strategies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com