Several explanations could be suggested for why NSAID therapy is less deleterious for fracture healing in some patients than in others.
Above 10 15 CPD, the L C model specifies an inverse delivery rate effect, whereby smoking more CPD for shorter duration is less deleterious (per cigarette) than smoking fewer CPD for longer duration, a pattern consistent with 'reduced potency' (Lubin and Caporaso, 2006).
The present findings indicate that continuous maternal EC exposure before and during gestation, are less deleterious for fetal ovarian development than a change in maternal EC exposure between pre and post-conception.
Recently, however, it has been suggested that biopsy of cells at other developmental stages may be less deleterious for the early embryo.
If it happens that a foreign protein is matured in a more appropriate manner in the urothelium than in the mammary gland, or if the resulting side effects of the protein are less deleterious for the animals, a system using expression in the urothelium may be useful [ 26].
Slower rates of inbreeding for example are expected to be less deleterious than faster inbreeding rates, allowing greater opportunity for selection to act before a given level of genetic diversity is lost.
These data demonstrate that the addition of a Y Sry- chromosome is deleterious for female fertility and that Yd-1 and Yd-3 are less deleterious than Y Sry-.
Developing surgical training will shorten the learning curve, with less deleterious effects on patients during this period.
These data suggest that variations in promoters are less deleterious than in exons, which have much less heterozygosity.
Authors' response: Certainly, Alu insertions ale less deleterious than L1s, and it is also less easy to quantify their direct effects caused for example by alternative splicing.
