Sentence examples for for large phase from inspiring English sources

Development of novel antibiotics for VAP is hampered by the need for large phase 3 trials with mortality endpoints.

Ultimately however, there remains a need for large phase III clinical trials evaluating the efficacy of standard therapy plus SIR-spheres compared to standard therapy alone.

As will be discussed in detail below, the traditional regulatory pathway's requirement for large phase III programs is a challenge if we wish to have new agents developed in advance of widespread resistance.

This is particularly so for large phase angles, when the difference between the values of the J-integral for E 1  = 400 MPa (E 1/ E 2  = 0.2) and E 1  = 1000 MPa (E 1/ E 2  = 0.5) can be as much as over 50% at ψ  ≈ 80°, as opposed to 24% at ψ  ≈ 0° (Fig. 4).

If administration of allo-MSCs is found feasible and safe, SENECA will pave the way for larger phase II/III studies with therapeutic efficacy as the primary outcome.

(4) For larger phase error, the exponential function can be approximated with 4 piecewise lines and the fitting error is less than 5%.

We would also recommend that the need to assess treatment effects across subgroups be considered when designing the efficacy stopping rules for interim analyses of large phase III studies.

In particular, it focuses on the conceptual design of a new cooling system suited for the large phase 2 upgrade programmes, which will be validated with the construction of a common prototype in the next years.

The data from this vanguard study will be used to finalize planning for a large, phase III clinical trial designed to evaluate the effect of treatment on depressive symptoms, coronary events, and death.

Similarly, for moderately large phase variations, the projected CTF could better preserve the spatial resolution of the reconstructed images [27].

As a small team, we don't possess the capabilities to recruit participants for a large Phase III trial, which would involve activities such as collecting blood samples and dispensing medications to participants on a daily basis for almost a year.