Sentence examples for for large difficult from inspiring English sources

Several studies have since been conducted using EST plus LBD for large, difficult bile duct stones [ 10- 13, 21, 22].

Thus, our method is applicable to a variety of fields, including: 1) Detecting the deletions across multiple genomes, especially for the species with large, difficult-to-sequence genomes in population or comparative genomic studies.

Automatic partitioning algorithms for large models are difficult to design for two fundamental reasons.

The sample size of Journalism Online's data was small — about two dozen mostly small- and medium-size papers that had been charging readers for several months — so divining any potential pattern for large newspapers is difficult.

Mr. Barnett said in an interview that, with construction financing for large projects still difficult to obtain, he believes his building is years ahead of anything comparable entering the market.

However, the use of these matrices for real-world applications is limited for several reasons: no fast matrix multiplication algorithm is available, huge memory requirements for large scale problems, difficult implementation on hardware, etc.

While RSA method is based on the fact that prime factorization for large integers is difficult, ElGamal signature method is based on the fact that solving discrete logarithm problem in large prime number is difficult.

Furthermore, this simple single-step immunoaffinity purification to high purity of membrane protein could be useful broadly for other membrane protein purifications, thus accelerating the determination of structures for large numbers of difficult-to-obtain membrane proteins.

"It's very difficult for large organizations to act like entrepreneurs.

It is now very difficult for large companies to lay off unneeded workers.

The Treasury moved yesterday to make it more difficult for large corporations to hide abusive tax-avoidance transactions.