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Two major points in the management of these patients are: 1) regular assessment of the efficacy of replacement therapy using clinical assessment and monitoring of coagulation parameters, and 2) the use of an appropriate transfusion protocol with guidelines for its proper implementation.
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Fundamental mechanisms behind the molten core cooling strategies are revisited to provide an insight for a proper implementation of severe accident management guideline (SAMG) and a development of an engineered safety feature.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com