Sentence examples for for its activation from inspiring English sources

In fact, cleavage of caspase-9 is not only unnecessary for its activation but it is also insufficient to produce an active enzyme.

ZD9331, a highly specific TS inhibitor that does not require polyglutamation for its activation, has shown activity in patients with refractory ovarian and colorectal cancer.

C-terminal phosphorylation of IRF3 is a critical step for its activation since it allows its homodimerization and nuclear translocation.

All Ifacthee nodes wake up after every sync pulse, and listen for the first 8 slots in a cycle.

It requires high (micromolar) cytosolic Ca2+ for its activation [ 231].

We also found that the RA-domain of PI3Kγ has no effect on channel activity, suggesting that PI3Kγ may tether to CNGA1 for its activation.

This receptor's function is further obscured as it has become clear that internalisation has to take place for its activation (Kim et al, 2003).

The Senegal striker's contract contains a release clause enabling him to leave Tyneside for £7m but Ba has not angled for its activation.

This poor response might be due to the requirement of specific enzymes for its activation.

They define the molecular signatures of the phenotype and demonstrate the requirement of TREM2 and APOE for its activation.

Cavrak, V. V. et al. How a retrotransposon exploits the plant's heat stress response for its activation.